University system culture is coherent and connective with university students’ cultivation education. It is not only the premise and the foundation of the cultivation education, but also the result of exploring the laws of the cultivation education. The influential factors of university system culture on university students’ cultivation education can be explored by optimizing and blending system culture for the propulsion of system culture construction, examining and innovating university philosophy for the cultivation of university students’ humanistic spirit, adjusting and integrating of the cultural psychology of modern university system.